Unable to walk after Moxidectin (ProHeart 6) in dogs

30 reports to the FDA describe unable to walk in dogs given Moxidectin. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported less often than average with this medicine.

30Reports
97%Marked serious
17%Recovered
17%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
16 59%
1–2 days
8 30%
3–7 days
2 7.4%
1–4 weeks
0 0.0%
Over a month
1 3.7%

How the animals did

Recovered
5 17%
Still unwell when reported
17 57%
Died
2 6.7%
Euthanised
3 10%
Not known
3 10%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
10
4–7 years
3
8–11 years
10
12+ years
5

About this medicine

Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).

Products with this ingredient include ProHeart 6, ProHeart 12. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Moxidectin cause unable to walk in dogs?
30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to walk with similar medicines

All reported side effects of Moxidectin in dogs · Medicines most reported with unable to walk