Misoprostol side effects in dogs

62 reports sent to the FDA between 2012 and 2025 involve Misoprostol in dogs. The most reported problems were loss of appetite, vomiting, lethargy. 56% were marked serious.

62Reports
56%Marked serious
0.0%Only medicine involved
13%Recovered
39%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

28 45%
25 40%
Diarrhea
18 29%
Kidney problems
17 27%
Hypoalbuminaemia
11 18%
Leucocytosis
10 16%
Blood in stool
10 16%
Hypoproteinaemia
10 16%
Abnormal ultrasound finding
9 15%
Decreased packed cell volume (pcv)
9 15%
Neutrophilia
8 13%
Loose stool
8 13%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
3 4.8%

How soon problems started

Same day
12 20%
1–2 days
13 22%
3–7 days
8 14%
1–4 weeks
14 24%
Over a month
12 20%

Time from the first dose to the first sign, where both dates were reported (59 reports).

How the animals did

Recovered
7 11%
Recovered with lasting effects
1 1.6%
Still unwell when reported
23 37%
Died
4 6.5%
Euthanised
20 32%
Not known
7 11%

Breeds named most often

Popular breeds appear more often because there are more of them.

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