Lethargy after Milk Thistle in dogs

The FDA has received 44 reports of lethargy in dogs after Milk Thistle. That is 31% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports
66%Marked serious
20%Recovered
18%Died or euthanised
46 daysTypical onset
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How soon it started

Same day
2 6.1%
1–2 days
3 9.1%
3–7 days
6 18%
1–4 weeks
1 3.0%
Over a month
21 64%

How the animals did

Recovered
8 18%
Recovered with lasting effects
1 2.3%
Still unwell when reported
16 36%
Died
5 11%
Euthanised
3 6.8%
Not known
11 25%

Problems reported at the same time

18 41%
Kidney problems
10 23%
Diarrhea
10 23%
Blood problems
9 20%
8 18%

Age of the animals

Under 1 year
1
1–3 years
5
4–7 years
8
8–11 years
11
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Milk Thistle cause lethargy in dogs?
44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 46 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Milk Thistle in dogs · Medicines most reported with lethargy