Hypothermia after Midazolam in dogs

40 reports to the FDA describe hypothermia in dogs given Midazolam. That is 3.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
85%Marked serious
35%Recovered
40%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
13 45%
1–2 days
7 24%
3–7 days
3 10%
1–4 weeks
0 0.0%
Over a month
6 21%

How the animals did

Recovered
14 35%
Still unwell when reported
7 18%
Died
9 23%
Euthanised
7 18%
Not known
3 7.5%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
9
4–7 years
13
8–11 years
12
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause hypothermia in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypothermia with similar medicines

All reported side effects of Midazolam in dogs · Medicines most reported with hypothermia