Hypothermia after Melarsomine (Immiticide) in dogs

174 reports to the FDA describe hypothermia in dogs given Melarsomine. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

174Reports
49%Marked serious
15%Recovered
20%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
52 50%
1–2 days
10 9.6%
3–7 days
12 12%
1–4 weeks
12 12%
Over a month
18 17%

How the animals did

Recovered
26 15%
Still unwell when reported
48 28%
Died
26 15%
Euthanised
8 4.6%
Not known
66 38%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
85
4–7 years
55
8–11 years
21
12+ years
5

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hypothermia in dogs?
174 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypothermia with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with hypothermia