Uncoded sign after Melarsomine (Immiticide) in dogs

62 reports to the FDA describe uncoded sign in dogs given Melarsomine. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

62Reports

82%Marked serious

19%Recovered

11%Died or euthanised

28 daysTypical onset

How soon it started

Same day

8 14%

1–2 days

6 11%

3–7 days

2 3.6%

1–4 weeks

23 41%

Over a month

17 30%

How the animals did

Recovered

11 18%

Recovered with lasting effects

1 1.6%

Still unwell when reported

13 21%

Died

4 6.5%

Euthanised

3 4.8%

Not known

30 48%

Problems reported at the same time

Swelling

15 24%

Injection site reaction

13 21%

11 18%

11 18%

9 15%

8 13%

8 13%

7 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause uncoded sign in dogs?: 62 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 28 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Melarsomine in dogs · Medicines most reported with uncoded sign