Tachycardia after Melarsomine (Immiticide) in dogs

385 reports to the FDA describe tachycardia in dogs given Melarsomine. That is 1.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

385Reports

51%Marked serious

15%Recovered

12%Died or euthanised

5 daysTypical onset

How soon it started

Same day

89 39%

1–2 days

14 6.2%

3–7 days

29 13%

1–4 weeks

40 18%

Over a month

55 24%

How the animals did

Recovered

57 15%

Recovered with lasting effects

1 0.3%

Still unwell when reported

94 24%

Died

39 10%

Euthanised

9 2.3%

Not known

185 48%

Problems reported at the same time

143 37%

105 27%

83 22%

71 18%

63 16%

62 16%

60 16%

55 14%

Age of the animals

Under 1 year

1–3 years

149

4–7 years

154

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause tachycardia in dogs?: 385 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tachycardia with similar medicines

Tachycardia after Polysulfated Glycosaminoglycan 41 reports · 0.8% of its reports
Tachycardia after Diphenhydramine 141 reports · 3.0% of its reports
Tachycardia after Butorphanol 192 reports · 4.3% of its reports
Tachycardia after Cefpodoxime 44 reports · 1.1% of its reports
Tachycardia after Tramadol 77 reports · 2.0% of its reports
Tachycardia after Desoxycorticosterone Pivalate 33 reports · 1.0% of its reports
Tachycardia after Propofol 143 reports · 4.7% of its reports
Tachycardia after Isoflurane 135 reports · 4.9% of its reports
Tachycardia after Cephalexin 21 reports · 0.8% of its reports
Tachycardia after Atipamezole 123 reports · 4.6% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with tachycardia