Neurological signs after Melarsomine (Immiticide) in dogs

The FDA has received 79 reports of neurological signs in dogs after Melarsomine. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

79Reports

37%Marked serious

5.1%Recovered

24%Died or euthanised

1 daysTypical onset

How soon it started

Same day

11 38%

1–2 days

8 28%

3–7 days

1 3.4%

1–4 weeks

4 14%

Over a month

5 17%

How the animals did

Recovered

3 3.8%

Recovered with lasting effects

1 1.3%

Still unwell when reported

11 14%

Died

13 16%

Euthanised

6 7.6%

Not known

45 57%

Problems reported at the same time

19 24%

18 23%

17 22%

13 16%

12 15%

11 14%

Proprioception abnormality

10 13%

Vomiting

10 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause neurological signs in dogs?: 79 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neurological signs with similar medicines

Neurological signs after Polysulfated Glycosaminoglycan 26 reports · 0.5% of its reports
Neurological signs after Diphenhydramine 24 reports · 0.5% of its reports
Neurological signs after Butorphanol 22 reports · 0.5% of its reports
Neurological signs after Cefpodoxime 24 reports · 0.6% of its reports
Neurological signs after Tramadol 30 reports · 0.8% of its reports
Neurological signs after Florfenicol + Mometasone + Terbinafine 23 reports · 0.6% of its reports
Neurological signs after Cephalexin 21 reports · 0.8% of its reports
Neurological signs after Famotidine 26 reports · 1.0% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with neurological signs