Muscle wasting after Melarsomine (Immiticide) in dogs

The FDA has received 28 reports of muscle wasting in dogs after Melarsomine. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

28Reports
43%Marked serious
3.6%Recovered
7.1%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
1 7.1%
1–2 days
1 7.1%
3–7 days
2 14%
1–4 weeks
6 43%
Over a month
4 29%

How the animals did

Recovered with lasting effects
1 3.6%
Still unwell when reported
5 18%
Died
1 3.6%
Euthanised
1 3.6%
Not known
20 71%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
12
4–7 years
10
8–11 years
3
12+ years
1

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause muscle wasting in dogs?
28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Muscle wasting with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with muscle wasting