Hypertension after Melarsomine (Immiticide) in dogs

38 reports to the FDA describe hypertension in dogs given Melarsomine. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

38Reports

84%Marked serious

18%Recovered

13%Died or euthanised

Same dayTypical onset

How soon it started

Same day

16 52%

1–2 days

1 3.2%

3–7 days

4 13%

1–4 weeks

2 6.5%

Over a month

8 26%

How the animals did

Recovered

7 18%

Still unwell when reported

15 39%

Died

2 5.3%

Euthanised

3 7.9%

Not known

11 29%

Problems reported at the same time

13 34%

11 29%

10 26%

10 26%

10 26%

9 24%

7 18%

7 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hypertension in dogs?: 38 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypertension with similar medicines

Hypertension after Diphenhydramine 27 reports · 0.6% of its reports
Hypertension after Butorphanol 40 reports · 0.9% of its reports
Hypertension after Tramadol 23 reports · 0.6% of its reports
Hypertension after Desoxycorticosterone Pivalate 26 reports · 0.8% of its reports
Hypertension after Propofol 27 reports · 0.9% of its reports
Hypertension after Isoflurane 25 reports · 0.9% of its reports
Hypertension after Famotidine 36 reports · 1.4% of its reports
Hypertension after Enalapril 23 reports · 1.4% of its reports
Hypertension after Midazolam 22 reports · 1.8% of its reports
Hypertension after Ampicillin 22 reports · 2.3% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with hypertension