Decreased urine concentration after Melarsomine (Immiticide) in dogs

60 reports to the FDA describe decreased urine concentration in dogs given Melarsomine. That is 0.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

60Reports

25%Marked serious

5.0%Recovered

5.0%Died or euthanised

13 daysTypical onset

How soon it started

Same day

2 10%

1–2 days

3 15%

3–7 days

2 10%

1–4 weeks

8 40%

Over a month

5 25%

How the animals did

Recovered

2 3.3%

Recovered with lasting effects

1 1.7%

Still unwell when reported

8 13%

Died

3 5.0%

Not known

46 77%

Problems reported at the same time

25 42%

21 35%

18 30%

17 28%

16 27%

15 25%

13 22%

12 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause decreased urine concentration in dogs?: 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased urine concentration with similar medicines

Decreased urine concentration after Polysulfated Glycosaminoglycan 49 reports · 0.9% of its reports
Decreased urine concentration after Diphenhydramine 31 reports · 0.7% of its reports
Decreased urine concentration after Butorphanol 29 reports · 0.7% of its reports
Decreased urine concentration after Cefpodoxime 58 reports · 1.4% of its reports
Decreased urine concentration after Tramadol 77 reports · 2.0% of its reports
Decreased urine concentration after Desoxycorticosterone Pivalate 92 reports · 2.8% of its reports
Decreased urine concentration after Dirlotapide 23 reports · 0.8% of its reports
Decreased urine concentration after Isoflurane 27 reports · 1.0% of its reports
Decreased urine concentration after Cephalexin 31 reports · 1.2% of its reports
Decreased urine concentration after Famotidine 44 reports · 1.7% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with decreased urine concentration