Arrhythmia after Melarsomine (Immiticide) in dogs

The FDA has received 40 reports of arrhythmia in dogs after Melarsomine. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause arrhythmia in dogs?

40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 7 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Arrhythmia with similar medicines

• Arrhythmia after Butorphanol 50 reports · 1.1% of its reports
• Arrhythmia after Tramadol 20 reports · 0.5% of its reports
• Arrhythmia after Propofol 52 reports · 1.7% of its reports
• Arrhythmia after Isoflurane 44 reports · 1.6% of its reports
• Arrhythmia after Atipamezole 32 reports · 1.2% of its reports
• Arrhythmia after Medetomidine 31 reports · 1.5% of its reports
• Arrhythmia after Sevoflurane 20 reports · 2.4% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with arrhythmia