Kidney problems after Lufenuron in dogs

25 reports to the FDA describe kidney problems in dogs given Lufenuron. That is 2.5% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

25Reports

4.0%Marked serious

0.0%Recovered

64%Died or euthanised

–Typical onset

How the animals did

Still unwell when reported

1 4.0%

Died

16 64%

Not known

8 32%

Problems reported at the same time

14 56%

13 52%

12 48%

9 36%

9 36%

9 36%

5 20%

Hyperglycaemia

3 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing.

Questions owners ask

Can Lufenuron cause kidney problems in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Spinosad (Comfortis) 439 reports · 0.8% of its reports
Kidney problems after Lufenuron + Milbemycin Oxime (Sentinel) 162 reports · 0.6% of its reports
Kidney problems after Imidacloprid + Moxidectin (Advantage Multi) 106 reports · 0.8% of its reports
Kidney problems after Nitenpyram (Capstar) 55 reports · 0.5% of its reports
Kidney problems after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 46 reports · 0.5% of its reports
Kidney problems after Fipronil + S-methoprene (Frontline Plus) 31 reports · 1.0% of its reports
Kidney problems after Flumethrin + Imidacloprid (Seresto) 27 reports · 1.2% of its reports
Kidney problems after Fipronil 30 reports · 2.1% of its reports

All reported side effects of Lufenuron in dogs · Medicines most reported with kidney problems