Accidental exposure after Lotilaner (Credelio) in dogs

60 reports to the FDA describe accidental exposure in dogs given Lotilaner. That is 0.6% of all reports for this medicine, compared with 1.5% across reports for all dog medicines, so it is reported less often than average with this medicine.

60Reports
15%Marked serious
38%Recovered
1.7%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
34 62%
1–2 days
10 18%
3–7 days
1 1.8%
1–4 weeks
5 9.1%
Over a month
5 9.1%

How the animals did

Recovered
23 38%
Still unwell when reported
27 45%
Died
1 1.7%
Not known
9 15%

Problems reported at the same time

Age of the animals

Under 1 year
12
1–3 years
23
4–7 years
7
8–11 years
10
12+ years
3

About this medicine

Lotilaner kills fleas and ticks; monthly chewable.

Products with this ingredient include Credelio. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Lotilaner cause accidental exposure in dogs?
60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Accidental exposure with similar medicines

All reported side effects of Lotilaner in dogs · Medicines most reported with accidental exposure