Pain after Lokivetmab (Cytopoint) in dogs

The FDA has received 119 reports of pain in dogs after Lokivetmab. That is 1.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

119Reports

70%Marked serious

7.6%Recovered

23%Died or euthanised

3 daysTypical onset

How soon it started

Same day

31 32%

1–2 days

17 17%

3–7 days

10 10%

1–4 weeks

12 12%

Over a month

28 29%

How the animals did

Recovered

9 7.6%

Still unwell when reported

64 54%

Died

9 7.6%

Euthanised

18 15%

Not known

19 16%

Problems reported at the same time

Lethargy

49 41%

Loss of appetite

49 41%

Death

27 23%

Didn't work as expected

24 20%

23 19%

23 19%

21 18%

19 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause pain in dogs?: 119 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Bedinvetmab (Librela) 577 reports · 2.9% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with pain