Neoplasia after Lokivetmab (Cytopoint) in dogs

The FDA has received 43 reports of neoplasia in dogs after Lokivetmab. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

100%Marked serious

2.3%Recovered

14%Died or euthanised

153 daysTypical onset

How soon it started

Same day

1 5.6%

1–2 days

0 0.0%

3–7 days

0 0.0%

1–4 weeks

3 17%

Over a month

14 78%

How the animals did

Recovered

1 2.3%

Still unwell when reported

30 70%

Died

1 2.3%

Euthanised

5 12%

Not known

6 14%

Problems reported at the same time

Didn't work as expected

13 30%

Dermal mass

7 16%

Death

6 14%

Lethargy

5 12%

Abnormal radiograph finding

5 12%

Liver problems

4 9.3%

Loss of appetite

4 9.3%

Abnormal cytology

4 9.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause neoplasia in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 153 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neoplasia with similar medicines

Neoplasia after Bedinvetmab (Librela) 64 reports · 0.3% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with neoplasia