Monocytosis after Lokivetmab (Cytopoint) in dogs

93 reports to the FDA describe monocytosis in dogs given Lokivetmab. That is 1.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

93Reports

87%Marked serious

6.5%Recovered

29%Died or euthanised

14 daysTypical onset

How soon it started

Same day

16 20%

1–2 days

9 11%

3–7 days

6 7.6%

1–4 weeks

22 28%

Over a month

26 33%

How the animals did

Recovered

6 6.5%

Still unwell when reported

54 58%

Died

11 12%

Euthanised

16 17%

Not known

6 6.5%

Problems reported at the same time

54 58%

52 56%

45 48%

42 45%

39 42%

37 40%

29 31%

27 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause monocytosis in dogs?: 93 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

Monocytosis after Bedinvetmab (Librela) 180 reports · 0.9% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with monocytosis