Lateral recumbency after Lokivetmab (Cytopoint) in dogs

The FDA has received 44 reports of lateral recumbency in dogs after Lokivetmab. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports

98%Marked serious

30%Recovered

45%Died or euthanised

1 daysTypical onset

How soon it started

Same day

19 48%

1–2 days

5 13%

3–7 days

2 5.0%

1–4 weeks

6 15%

Over a month

8 20%

How the animals did

Recovered

13 30%

Still unwell when reported

9 20%

Died

11 25%

Euthanised

9 20%

Not known

2 4.5%

Problems reported at the same time

20 45%

18 41%

17 39%

15 34%

14 32%

11 25%

9 20%

8 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause lateral recumbency in dogs?: 44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lateral recumbency with similar medicines

Lateral recumbency after Bedinvetmab (Librela) 202 reports · 1.0% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with lateral recumbency