Lateral recumbency after Bedinvetmab (Librela) in dogs

The FDA has received 202 reports of lateral recumbency in dogs after Bedinvetmab. That is 1.0% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

202Reports

93%Marked serious

11%Recovered

54%Died or euthanised

4 daysTypical onset

How soon it started

Same day

41 24%

1–2 days

33 19%

3–7 days

21 12%

1–4 weeks

40 23%

Over a month

36 21%

How the animals did

Recovered

23 11%

Still unwell when reported

63 31%

Died

31 15%

Euthanised

79 39%

Not known

6 3.0%

Problems reported at the same time

110 54%

56 28%

54 27%

51 25%

51 25%

45 22%

45 22%

40 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

117

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause lateral recumbency in dogs?: 202 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lateral recumbency with similar medicines

Lateral recumbency after Lokivetmab (Cytopoint) 44 reports · 0.7% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with lateral recumbency