Intentional misuse after Lokivetmab (Cytopoint) in dogs

The FDA has received 111 reports of intentional misuse in dogs after Lokivetmab. That is 1.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

111Reports

77%Marked serious

8.1%Recovered

13%Died or euthanised

5 daysTypical onset

How soon it started

Same day

28 30%

1–2 days

12 13%

3–7 days

11 12%

1–4 weeks

16 17%

Over a month

25 27%

How the animals did

Recovered

9 8.1%

Still unwell when reported

78 70%

Died

7 6.3%

Euthanised

7 6.3%

Not known

10 9.0%

Problems reported at the same time

Didn't work as expected

56 50%

23 21%

19 17%

15 14%

14 13%

13 12%

13 12%

12 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause intentional misuse in dogs?: 111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Intentional misuse with similar medicines

Intentional misuse after Bedinvetmab (Librela) 448 reports · 2.3% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with intentional misuse