Injection site reaction after Lokivetmab (Cytopoint) in dogs

The FDA has received 96 reports of injection site reaction in dogs after Lokivetmab. That is 1.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

96Reports

43%Marked serious

9.4%Recovered

8.3%Died or euthanised

12 daysTypical onset

How soon it started

Same day

19 24%

1–2 days

10 13%

3–7 days

4 5.1%

1–4 weeks

22 28%

Over a month

23 29%

How the animals did

Recovered

8 8.3%

Recovered with lasting effects

1 1.0%

Still unwell when reported

60 63%

Died

5 5.2%

Euthanised

3 3.1%

Not known

19 20%

Problems reported at the same time

Didn't work as expected

28 29%

27 28%

26 27%

24 25%

15 16%

14 15%

14 15%

Skin rash or irritation

11 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause injection site reaction in dogs?: 96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Bedinvetmab (Librela) 299 reports · 1.5% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with injection site reaction