Injection site reaction after Bedinvetmab (Librela) in dogs

The FDA has received 299 reports of injection site reaction in dogs after Bedinvetmab. That is 1.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

299Reports

57%Marked serious

21%Recovered

7.4%Died or euthanised

3 daysTypical onset

How soon it started

Same day

99 37%

1–2 days

34 13%

3–7 days

43 16%

1–4 weeks

42 16%

Over a month

52 19%

How the animals did

Recovered

60 20%

Recovered with lasting effects

2 0.7%

Still unwell when reported

181 61%

Died

9 3.0%

Euthanised

13 4.3%

Not known

34 11%

Problems reported at the same time

52 17%

41 14%

36 12%

29 9.7%

25 8.4%

22 7.4%

22 7.4%

21 7.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

122

12+ years

133

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause injection site reaction in dogs?: 299 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Lokivetmab (Cytopoint) 96 reports · 1.5% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with injection site reaction