Adipsia after Lokivetmab (Cytopoint) in dogs

The FDA has received 38 reports of adipsia in dogs after Lokivetmab. That is 0.6% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

38Reports

61%Marked serious

11%Recovered

13%Died or euthanised

1 daysTypical onset

How soon it started

Same day

11 30%

1–2 days

12 32%

3–7 days

4 11%

1–4 weeks

5 14%

Over a month

5 14%

How the animals did

Recovered

4 11%

Still unwell when reported

21 55%

Died

1 2.6%

Euthanised

4 11%

Not known

8 21%

Problems reported at the same time

Loss of appetite

35 92%

Lethargy

25 66%

Vomiting

13 34%

Didn't work as expected

9 24%

7 18%

7 18%

6 16%

6 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause adipsia in dogs?: 38 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Adipsia with similar medicines

Adipsia after Bedinvetmab (Librela) 60 reports · 0.3% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with adipsia