Pyoderma after Leptospirosis Vaccine in dogs

20 reports to the FDA describe pyoderma in dogs given Leptospirosis Vaccine. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

20Reports

45%Marked serious

10%Recovered

10%Died or euthanised

21 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

3 17%

3–7 days

1 5.6%

1–4 weeks

6 33%

Over a month

6 33%

How the animals did

Recovered

2 10%

Still unwell when reported

12 60%

Euthanised

2 10%

Not known

4 20%

Problems reported at the same time

Vomiting

9 45%

Itching

9 45%

Didn't work as expected

7 35%

7 35%

6 30%

6 30%

6 30%

Skin rash or irritation

5 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause pyoderma in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pyoderma with similar medicines

Pyoderma after Rabies Vaccine 33 reports · 0.3% of its reports
Pyoderma after Distemper-parvo Vaccine 22 reports · 0.3% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with pyoderma