Squinting after Ketoconazole in dogs

30 reports to the FDA describe squinting in dogs given Ketoconazole. That is 1.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

80%Marked serious

33%Recovered

0.0%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 48%

1–2 days

5 20%

3–7 days

2 8.0%

1–4 weeks

5 20%

Over a month

1 4.0%

How the animals did

Recovered

8 27%

Recovered with lasting effects

2 6.7%

Still unwell when reported

15 50%

Not known

5 17%

Problems reported at the same time

Ocular discharge

18 60%

Corneal ulcer

14 47%

Neurogenic keratoconjunctivitis sicca (kcs)

14 47%

Schirmer tear test

10 33%

Keratoconjunctivitis sicca

9 30%

Loss of appetite

9 30%

Dry eye

8 27%

Abnormal schirmer tear test

8 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause squinting in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Squinting with similar medicines

Squinting after Florfenicol + Mometasone + Terbinafine 162 reports · 4.6% of its reports
Squinting after Betamethasone + Florfenicol + Terbinafine 27 reports · 1.1% of its reports
Squinting after Pilocarpine 26 reports · 33% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with squinting