Schirmer tear test after Ketoconazole in dogs

The FDA has received 34 reports of schirmer tear test in dogs after Ketoconazole. That is 1.5% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports

79%Marked serious

24%Recovered

2.9%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 46%

1–2 days

7 27%

3–7 days

4 15%

1–4 weeks

1 3.8%

Over a month

2 7.7%

How the animals did

Recovered

8 24%

Still unwell when reported

18 53%

Euthanised

1 2.9%

Not known

7 21%

Problems reported at the same time

Corneal ulcer

20 59%

Ocular discharge

18 53%

Keratoconjunctivitis sicca

15 44%

Loss of appetite

12 35%

Blepharospasm

11 32%

Vomiting

11 32%

Neurogenic keratoconjunctivitis sicca (kcs)

11 32%

Dry eye

10 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause schirmer tear test in dogs?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Schirmer tear test with similar medicines

Schirmer tear test after Florfenicol + Mometasone + Terbinafine 156 reports · 4.4% of its reports
Schirmer tear test after Betamethasone + Florfenicol + Terbinafine 30 reports · 1.2% of its reports
Schirmer tear test after Pilocarpine 33 reports · 42% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with schirmer tear test