Squinting after Pilocarpine in dogs

The FDA has received 26 reports of squinting in dogs after Pilocarpine. That is 33% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

92%Marked serious

27%Recovered

7.7%Died or euthanised

1 daysTypical onset

How soon it started

Same day

11 48%

1–2 days

3 13%

3–7 days

0 0.0%

1–4 weeks

6 26%

Over a month

3 13%

How the animals did

Recovered

7 27%

Still unwell when reported

6 23%

Euthanised

2 7.7%

Not known

11 42%

Problems reported at the same time

18 69%

16 62%

13 50%

13 50%

12 46%

12 46%

Keratoconjunctivitis sicca

11 42%

Dry eye

11 42%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Pilocarpine cause squinting in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Squinting with similar medicines

Squinting after Florfenicol + Mometasone + Terbinafine 162 reports · 4.6% of its reports
Squinting after Betamethasone + Florfenicol + Terbinafine 27 reports · 1.1% of its reports
Squinting after Ketoconazole 30 reports · 1.3% of its reports

All reported side effects of Pilocarpine in dogs · Medicines most reported with squinting