Increased percentage reticulocytes after Isoflurane in dogs

23 reports to the FDA describe increased percentage reticulocytes in dogs given Isoflurane. That is 0.8% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

23Reports

87%Marked serious

13%Recovered

26%Died or euthanised

2 daysTypical onset

How soon it started

Same day

5 29%

1–2 days

5 29%

3–7 days

2 12%

1–4 weeks

4 24%

Over a month

1 5.9%

How the animals did

Recovered

3 13%

Still unwell when reported

6 26%

Died

2 8.7%

Euthanised

4 17%

Not known

8 35%

Problems reported at the same time

18 78%

18 78%

13 57%

13 57%

12 52%

12 52%

11 48%

11 48%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause increased percentage reticulocytes in dogs?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased percentage reticulocytes with similar medicines

Increased percentage reticulocytes after Diphenhydramine 26 reports · 0.6% of its reports
Increased percentage reticulocytes after Butorphanol 20 reports · 0.5% of its reports
Increased percentage reticulocytes after Famotidine 22 reports · 0.8% of its reports
Increased percentage reticulocytes after Sucralfate 21 reports · 2.1% of its reports

All reported side effects of Isoflurane in dogs · Medicines most reported with increased percentage reticulocytes