Imidacloprid + Pyriproxyfen side effects in dogs
267 reports sent to the FDA between 2012 and 2026 involve Imidacloprid + Pyriproxyfen in dogs. The most reported problems were itching, vomiting, lethargy. 33% were marked serious.
267Reports
33%Marked serious
0.0%Only medicine involved
19%Recovered
5.2%Died or euthanised
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About this medicine
Imidacloprid kills fleas (spot-on or collar).
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (182 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Yorkshire Terrier 23 reports
- Pit Bull 15 reports
- Chihuahua 10 reports
- Labrador Retriever 9 reports
- German Pomeranian Spitz 7 reports
- German Shepherd Dog 7 reports
- Jack Russell Terrier 5 reports
- Shetland Sheepdog 5 reports
- Shih Tzu 5 reports
- Miniature Schnauzer 4 reports
Other flea and tick treatments for dogs
Spinosad (Comfortis)57,095 reports · 7.7% seriousLufenuron + Milbemycin Oxime (Sentinel)26,051 reports · 24% seriousImidacloprid + Moxidectin (Advantage Multi)13,117 reports · 57% seriousNitenpyram (Capstar)10,782 reports · 10.0% seriousLufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum)9,966 reports · 40% seriousFipronil + S-methoprene (Frontline Plus)2,954 reports · 49% seriousFlumethrin + Imidacloprid (Seresto)2,273 reports · 25% seriousImidacloprid1,908 reports · 11% serious