Neoplasia after Imidacloprid + Moxidectin (Advantage Multi) in dogs
25 reports to the FDA describe neoplasia in dogs given Imidacloprid + Moxidectin. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.
25Reports
92%Marked serious
8.0%Recovered
60%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause neoplasia in dogs?
- 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Neoplasia with similar medicines
- Neoplasia after Spinosad (Comfortis) 77 reports · 0.1% of its reports
- Neoplasia after Lufenuron + Milbemycin Oxime (Sentinel) 28 reports · 0.1% of its reports
All reported side effects of Imidacloprid + Moxidectin in dogs · Medicines most reported with neoplasia