Pancreatitis after Grapiprant (Galliprant) in dogs

114 reports to the FDA describe pancreatitis in dogs given Grapiprant. That is 1.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

114Reports
86%Marked serious
13%Recovered
28%Died or euthanised
20 daysTypical onset
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How soon it started

Same day
12 14%
1–2 days
13 15%
3–7 days
8 9.3%
1–4 weeks
13 15%
Over a month
40 47%

How the animals did

Recovered
14 12%
Recovered with lasting effects
1 0.9%
Still unwell when reported
42 37%
Died
7 6.1%
Euthanised
25 22%
Not known
25 22%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
10
8–11 years
47
12+ years
50

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause pancreatitis in dogs?
114 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pancreatitis with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with pancreatitis