Overdose after Grapiprant (Galliprant) in dogs

The FDA has received 109 reports of overdose in dogs after Grapiprant. That is 1.2% of all reports for this medicine, compared with 1.3% across reports for all dog medicines.

109Reports
46%Marked serious
23%Recovered
20%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
41 43%
1–2 days
15 16%
3–7 days
3 3.1%
1–4 weeks
10 10%
Over a month
27 28%

How the animals did

Recovered
24 22%
Recovered with lasting effects
1 0.9%
Still unwell when reported
42 39%
Died
3 2.8%
Euthanised
19 17%
Not known
20 18%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
8
4–7 years
7
8–11 years
41
12+ years
47

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause overdose in dogs?
109 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Overdose with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with overdose