Elevated cholesterol (total) after Grapiprant (Galliprant) in dogs
The FDA has received 65 reports of elevated cholesterol (total) in dogs after Grapiprant. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.
65Reports
68%Marked serious
4.6%Recovered
26%Died or euthanised
34 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).
Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.
Questions owners ask
- Can Grapiprant cause elevated cholesterol (total) in dogs?
- 65 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 34 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Elevated cholesterol (total) with similar medicines
- Elevated cholesterol (total) after Carprofen (Rimadyl) 694 reports · 1.5% of its reports
- Elevated cholesterol (total) after Deracoxib (Deramaxx) 178 reports · 1.6% of its reports
- Elevated cholesterol (total) after Meloxicam (Metacam) 54 reports · 0.7% of its reports
- Elevated cholesterol (total) after Firocoxib (Previcox) 63 reports · 0.8% of its reports
All reported side effects of Grapiprant in dogs · Medicines most reported with elevated cholesterol (total)