Blood in vomit after Grapiprant (Galliprant) in dogs

106 reports to the FDA describe blood in vomit in dogs given Grapiprant. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

106Reports
52%Marked serious
35%Recovered
12%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
12 14%
1–2 days
9 11%
3–7 days
19 23%
1–4 weeks
16 19%
Over a month
28 33%

How the animals did

Recovered
36 34%
Recovered with lasting effects
1 0.9%
Still unwell when reported
34 32%
Died
5 4.7%
Euthanised
8 7.5%
Not known
22 21%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
4
4–7 years
17
8–11 years
40
12+ years
43

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause blood in vomit in dogs?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in vomit with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with blood in vomit