Pacing after Fluralaner (Bravecto) in dogs

The FDA has received 187 reports of pacing in dogs after Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

187Reports
79%Marked serious
27%Recovered
16%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
47 43%
1–2 days
26 24%
3–7 days
9 8.3%
1–4 weeks
11 10%
Over a month
16 15%

How the animals did

Recovered
44 24%
Recovered with lasting effects
6 3.2%
Still unwell when reported
83 44%
Died
9 4.8%
Euthanised
21 11%
Not known
24 13%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
35
4–7 years
58
8–11 years
54
12+ years
33

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause pacing in dogs?
187 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pacing with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with pacing