Not himself/herself after Fluralaner (Bravecto) in dogs

313 reports to the FDA describe not himself/herself in dogs given Fluralaner. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

313Reports

58%Marked serious

18%Recovered

9.6%Died or euthanised

1 daysTypical onset

How soon it started

Same day

78 47%

1–2 days

43 26%

3–7 days

15 9.0%

1–4 weeks

13 7.8%

Over a month

17 10%

How the animals did

Recovered

53 17%

Recovered with lasting effects

3 1.0%

Still unwell when reported

201 64%

Died

10 3.2%

Euthanised

20 6.4%

Not known

26 8.3%

Problems reported at the same time

151 48%

103 33%

85 27%

58 19%

54 17%

43 14%

33 11%

31 9.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause not himself/herself in dogs?: 313 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not himself/herself with similar medicines

Not himself/herself after Afoxolaner (NexGard) 95 reports · 0.2% of its reports
Not himself/herself after Sarolaner (Simparica) 101 reports · 0.6% of its reports
Not himself/herself after Lotilaner (Credelio) 79 reports · 0.8% of its reports
Not himself/herself after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 58 reports · 0.6% of its reports
Not himself/herself after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 63 reports · 2.0% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with not himself/herself