Low platelet count after Fluralaner (Bravecto) in dogs

The FDA has received 177 reports of low platelet count in dogs after Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

177Reports
94%Marked serious
13%Recovered
29%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
29 29%
1–2 days
19 19%
3–7 days
10 10%
1–4 weeks
13 13%
Over a month
28 28%

How the animals did

Recovered
16 9.0%
Recovered with lasting effects
7 4.0%
Still unwell when reported
80 45%
Died
13 7.3%
Euthanised
39 22%
Not known
22 12%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
36
4–7 years
66
8–11 years
46
12+ years
18

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause low platelet count in dogs?
177 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with low platelet count