Fever after Fluralaner (Bravecto) in dogs

638 reports to the FDA describe fever in dogs given Fluralaner. That is 0.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

638Reports
93%Marked serious
20%Recovered
26%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
152 33%
1–2 days
126 27%
3–7 days
55 12%
1–4 weeks
45 9.8%
Over a month
82 18%

How the animals did

Recovered
117 18%
Recovered with lasting effects
9 1.4%
Still unwell when reported
271 42%
Died
56 8.8%
Euthanised
107 17%
Not known
78 12%

Problems reported at the same time

Age of the animals

Under 1 year
63
1–3 years
184
4–7 years
195
8–11 years
140
12+ years
53

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause fever in dogs?
638 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with fever