Discoloured urine after Fluralaner (Bravecto) in dogs

51 reports to the FDA describe discoloured urine in dogs given Fluralaner. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported less often than average with this medicine.

51Reports
94%Marked serious
3.9%Recovered
47%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
6 19%
1–2 days
7 22%
3–7 days
6 19%
1–4 weeks
6 19%
Over a month
7 22%

How the animals did

Recovered
2 3.9%
Still unwell when reported
22 43%
Died
8 16%
Euthanised
16 31%
Not known
3 5.9%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
11
4–7 years
15
8–11 years
15
12+ years
7

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause discoloured urine in dogs?
51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Discoloured urine with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with discoloured urine