Dehydration after Fluralaner (Bravecto) in dogs

381 reports to the FDA describe dehydration in dogs given Fluralaner. That is 0.6% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

381Reports

94%Marked serious

22%Recovered

23%Died or euthanised

1 daysTypical onset

How soon it started

Same day

71 28%

1–2 days

89 35%

3–7 days

22 8.6%

1–4 weeks

24 9.3%

Over a month

51 20%

How the animals did

Recovered

75 20%

Recovered with lasting effects

9 2.4%

Still unwell when reported

156 41%

Died

31 8.1%

Euthanised

55 14%

Not known

55 14%

Problems reported at the same time

248 65%

244 64%

233 61%

161 42%

116 30%

92 24%

86 23%

59 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

108

8–11 years

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause dehydration in dogs?: 381 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Afoxolaner (NexGard) 272 reports · 0.5% of its reports
Dehydration after Sarolaner (Simparica) 95 reports · 0.6% of its reports
Dehydration after Lotilaner (Credelio) 76 reports · 0.8% of its reports
Dehydration after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 47 reports · 0.5% of its reports
Dehydration after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 27 reports · 0.9% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with dehydration