Abnormal ultrasound finding after Fluralaner (Bravecto) in dogs

287 reports to the FDA describe abnormal ultrasound finding in dogs given Fluralaner. That is 0.4% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

287Reports
96%Marked serious
7.7%Recovered
41%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
36 18%
1–2 days
43 22%
3–7 days
24 12%
1–4 weeks
31 16%
Over a month
63 32%

How the animals did

Recovered
8 2.8%
Recovered with lasting effects
14 4.9%
Still unwell when reported
121 42%
Died
26 9.1%
Euthanised
91 32%
Not known
27 9.4%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
33
4–7 years
84
8–11 years
120
12+ years
39

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause abnormal ultrasound finding in dogs?
287 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with abnormal ultrasound finding