Collapse after Fluoxetine in dogs

The FDA has received 21 reports of collapse in dogs after Fluoxetine. That is 0.8% of all reports for this medicine, compared with 0.9% across reports for all dog medicines.

21Reports

86%Marked serious

29%Recovered

19%Died or euthanised

22 daysTypical onset

How soon it started

Same day

2 14%

1–2 days

1 7.1%

3–7 days

2 14%

1–4 weeks

3 21%

Over a month

6 43%

How the animals did

Recovered

6 29%

Still unwell when reported

6 29%

Died

2 9.5%

Euthanised

2 9.5%

Not known

5 24%

Problems reported at the same time

10 48%

8 38%

7 33%

4 19%

4 19%

4 19%

Abnormal radiograph finding

4 19%

Wobbliness (ataxia)

3 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause collapse in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Collapse with similar medicines

Collapse after Gabapentin 285 reports · 3.2% of its reports
Collapse after Selegiline (Anipryl) 61 reports · 1.5% of its reports
Collapse after Trazodone 77 reports · 3.0% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with collapse