Lethargy after Fluconazole in dogs

The FDA has received 60 reports of lethargy in dogs after Fluconazole. That is 19% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports
63%Marked serious
17%Recovered
17%Died or euthanised
20 daysTypical onset
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How soon it started

Same day
6 13%
1–2 days
5 11%
3–7 days
5 11%
1–4 weeks
9 20%
Over a month
21 46%

How the animals did

Recovered
9 15%
Recovered with lasting effects
1 1.7%
Still unwell when reported
29 48%
Died
4 6.7%
Euthanised
6 10%
Not known
11 18%

Problems reported at the same time

26 43%
19 32%
Blood problems
10 17%
10 17%

Age of the animals

Under 1 year
4
1–3 years
10
4–7 years
17
8–11 years
20
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Fluconazole cause lethargy in dogs?
60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Fluconazole in dogs · Medicines most reported with lethargy