Swelling after Estriol in dogs

The FDA has received 133 reports of swelling in dogs after Estriol. That is 6.6% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

133Reports
32%Marked serious
11%Recovered
3.8%Died or euthanised
26 daysTypical onset
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How soon it started

Same day
3 7.7%
1–2 days
2 5.1%
3–7 days
6 15%
1–4 weeks
12 31%
Over a month
16 41%

How the animals did

Recovered
14 11%
Still unwell when reported
25 19%
Died
2 1.5%
Euthanised
3 2.3%
Not known
89 67%

Problems reported at the same time

11 8.3%
Increased sexual interest
9 6.8%
Excessive licking and/or grooming
8 6.0%
7 5.3%
7 5.3%

Age of the animals

Under 1 year
1
1–3 years
15
4–7 years
40
8–11 years
25
12+ years
50

About this medicine

Type: medicine.

Questions owners ask

Can Estriol cause swelling in dogs?
133 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 26 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Estriol in dogs · Medicines most reported with swelling