Dehydration after Doxycycline in dogs

71 reports to the FDA describe dehydration in dogs given Doxycycline. That is 1.8% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

71Reports

85%Marked serious

5.6%Recovered

41%Died or euthanised

24 daysTypical onset

How soon it started

Same day

5 8.9%

1–2 days

6 11%

3–7 days

10 18%

1–4 weeks

9 16%

Over a month

26 46%

How the animals did

Recovered

3 4.2%

Recovered with lasting effects

1 1.4%

Still unwell when reported

27 38%

Died

12 17%

Euthanised

17 24%

Not known

11 15%

Problems reported at the same time

45 63%

42 59%

36 51%

35 49%

29 41%

26 37%

24 34%

20 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause dehydration in dogs?: 71 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 24 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Amoxicillin + Clavulanate (Clavamox) 150 reports · 2.8% of its reports
Dehydration after Cefovecin (Convenia) 104 reports · 2.7% of its reports
Dehydration after Enrofloxacin (Baytril) 130 reports · 3.4% of its reports
Dehydration after Metronidazole 163 reports · 5.3% of its reports
Dehydration after Amoxicillin 54 reports · 4.0% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with dehydration