Blood in urine after Doxycycline in dogs

The FDA has received 32 reports of blood in urine in dogs after Doxycycline. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports

84%Marked serious

0.0%Recovered

41%Died or euthanised

13 daysTypical onset

How soon it started

Same day

6 20%

1–2 days

3 10%

3–7 days

4 13%

1–4 weeks

6 20%

Over a month

11 37%

How the animals did

Still unwell when reported

17 53%

Died

6 19%

Euthanised

7 22%

Not known

2 6.3%

Problems reported at the same time

20 63%

19 59%

16 50%

16 50%

13 41%

12 38%

11 34%

9 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause blood in urine in dogs?: 32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in urine with similar medicines

Blood in urine after Amoxicillin + Clavulanate (Clavamox) 69 reports · 1.3% of its reports
Blood in urine after Cefovecin (Convenia) 22 reports · 0.6% of its reports
Blood in urine after Enrofloxacin (Baytril) 34 reports · 0.9% of its reports
Blood in urine after Metronidazole 26 reports · 0.8% of its reports
Blood in urine after Amoxicillin 27 reports · 2.0% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with blood in urine