Abdominal pain after Doxycycline in dogs

The FDA has received 25 reports of abdominal pain in dogs after Doxycycline. That is 0.6% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

25Reports

76%Marked serious

12%Recovered

44%Died or euthanised

27 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

1 4.8%

3–7 days

4 19%

1–4 weeks

6 29%

Over a month

10 48%

How the animals did

Recovered

3 12%

Still unwell when reported

7 28%

Died

2 8.0%

Euthanised

9 36%

Not known

4 16%

Problems reported at the same time

18 72%

15 60%

15 60%

14 56%

13 52%

11 44%

11 44%

11 44%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause abdominal pain in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abdominal pain with similar medicines

Abdominal pain after Amoxicillin + Clavulanate (Clavamox) 81 reports · 1.5% of its reports
Abdominal pain after Cefovecin (Convenia) 47 reports · 1.2% of its reports
Abdominal pain after Enrofloxacin (Baytril) 59 reports · 1.6% of its reports
Abdominal pain after Metronidazole 74 reports · 2.4% of its reports
Abdominal pain after Amoxicillin 32 reports · 2.4% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with abdominal pain