Elevated globulins after Distemper-parvo Vaccine in dogs

The FDA has received 54 reports of elevated globulins in dogs after Distemper-parvo Vaccine. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports
76%Marked serious
7.4%Recovered
31%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
5 11%
1–2 days
12 26%
3–7 days
9 20%
1–4 weeks
11 24%
Over a month
9 20%

How the animals did

Recovered
4 7.4%
Still unwell when reported
22 41%
Died
4 7.4%
Euthanised
13 24%
Not known
11 20%

Problems reported at the same time

Loss of appetite
37 69%
Lethargy
36 67%
Liver problems
29 54%
Blood problems
26 48%
Vomiting
25 46%
Death
17 31%
Leucocytosis
16 30%
Kidney problems
16 30%

Age of the animals

Under 1 year
7
1–3 years
7
4–7 years
18
8–11 years
15
12+ years
6

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Distemper-parvo Vaccine cause elevated globulins in dogs?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

All reported side effects of Distemper-parvo Vaccine in dogs · Medicines most reported with elevated globulins