Elevated globulins after Bordetella Vaccine in dogs

The FDA has received 97 reports of elevated globulins in dogs after Bordetella Vaccine. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports
78%Marked serious
9.3%Recovered
26%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
14 17%
1–2 days
16 19%
3–7 days
10 12%
1–4 weeks
26 31%
Over a month
17 20%

How the animals did

Recovered
8 8.2%
Recovered with lasting effects
1 1.0%
Still unwell when reported
46 47%
Died
7 7.2%
Euthanised
18 19%
Not known
17 18%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
21
4–7 years
28
8–11 years
27
12+ years
16

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause elevated globulins in dogs?
97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with elevated globulins