Elevated globulins after Rabies Vaccine in dogs

The FDA has received 97 reports of elevated globulins in dogs after Rabies Vaccine. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports
82%Marked serious
7.2%Recovered
25%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
11 14%
1–2 days
11 14%
3–7 days
20 25%
1–4 weeks
27 33%
Over a month
12 15%

How the animals did

Recovered
6 6.2%
Recovered with lasting effects
1 1.0%
Still unwell when reported
41 42%
Died
8 8.2%
Euthanised
16 16%
Not known
25 26%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
25
4–7 years
28
8–11 years
28
12+ years
10

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause elevated globulins in dogs?
97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with elevated globulins